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Sclerostin is a glycoprotein primarily produced by osteocytes, bone cells embedded within the bone matrix. It plays a crucial role in regulating bone metabolism by acting as Wnt signaling pathway antagonist, essential for promoting bone formation. By inhibiting this pathway, sclerostin effectively reduces osteoblast activity and bone formation, thereby maintaining a balance between bone growth [...]

About Dickkopf-1 (DKK-1)  - a  key regulator of the Wnt signaling pathway DKK-1 is a protein that functions as a key regulator of the Wnt signaling pathway, which is essential for various cellular processes including growth, development, and tissue homeostasis. DKK-1 primarily acts as an antagonist of the Wnt pathway by binding to specific receptors, [...]

During Breast Cancer Awareness Month, let´s share insights on emerging biomarkers such as PERIOSTIN that offer potential for improved diagnosis, prognosis, and personalized therapy. PERIOSTIN is a potential marker for breast cancer progression  Periostin is a matricellular protein that plays a significant role in the progression of breast cancer. Several studies have demonstrated that Periostin [...]