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Exploring FGF23 Regulation in Kidney Failure - Fibroblast growth factor 23 (FGF23) is a key hormone that is involved in the regulation of mineral metabolism, particularly regulating phosphate balance (1). In patients with end-stage kidney disease (ESKD), circulating FGF23 levels are markedly elevated and have been independently associated with increased mortality (2). However, the mechanisms [...]

Breast cancer is the most commonly diagnosed cancer in women worldwide and remains a leading cause of cancer-related death. While treatment options have improved significantly, advanced breast cancer is still difficult to manage, highlighting the need for reliable biomarkers to monitor treatment response and support clinical decision-making (1-3). PERIOSTIN - A Biomarker for Chemotherapy Response [...]

About Osteoporosis Osteoporosis is a bone condition where bone loss progresses gradually without symptoms until a fracture occurs. It develops when bone mineral density and bone strength decline, making bones more fragile and more likely to break (1, 2 ). Worldwide, osteoporosis and related fragility fractures are a major public health concern. About 1 in [...]