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FGF23 Reveals Mineral Imbalance in Hypoparathyroidism - Hypoparathyroidism (HypoPT) is a rare endocrine condition marked by inadequate or absent production of parathyroid hormone (PTH), leading to low calcium levels (hypocalcemia), elevated phosphate levels (hyperphosphatemia), and disturbed calcium-phosphate balance (1, 2). When this deficiency persists over the long term, it is referred to as chronic hypoparathyroidism, which [...]

Periostin - A Serum Biomarker for Osteogenesis Imperfecta Progression Osteogenesis Imperfecta (OI), also known as brittle bone disease, is a genetic disorder characterized by fragile bones that break easily, often with little or no apparent cause. It is caused by mutations in the genes responsible for producing collagen, a vital protein for bone strength and [...]

Type 2 Diabetes Mellitus (T2DM) and Cardiovascular (CV) diseases Patients with T2DM have an elevated risk of developing CV diseases due to multiple factors. Chronic hyperglycemia, or elevated blood sugar levels, can cause damage to blood vessels promoting the development of atherosclerosis (1). Insulin resistance, a hallmark of T2DM, contributes to abnormal lipid profiles, such [...]