Endostatin – a useful biomarker predicting mortality in AKI
Acute kidney injury (AKI) is an abrupt loss of kidney function and is independently associated with high mortality in critically ill patients. Endostatin, the C-terminal proteolytic fragment of collagen XVIII, is expressed during the progression of renal fibrosis. A team of researchers recently demonstrated that serial measurement of plasma endostatin has useful predictive value for 30-day mortality in AKI patients.
Read more: Prognostic value of dynamic plasma endostatin for the prediction of mortality in acute kidney injury: A prospective cohort study. Jia HM et al., J Int Med Res. 2020 48(7):300060520940856. Full text
Endostatin can reliably be measured by ELISA in human serum, plasma and urine samples. Only 20 µl of sample volume is required!
Endostatin ELISA Assay Highlights: https://www.bmgrp.com/product/cardiovascular/human-endostatin-elisa-biomedica/
• SPECIFIC – no cross-reactivity with COL15A1
• CONVENIENT – Assay range optimized for clinical samples
• RELIABLE – Validated according to international quality guidelines
• EASY – Results in 4,5 h, all reagents included