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Periostin is a Novel Itch Mediator
Chronic allergic itch is a common symptom affecting millions of people, but its pathogenesis is not fully understood. Periostin is an extracellular matrix protein that is highly expressed in the skin. Researchers have identified that Periostin can directly activate itch-associated neurons in the skin. Blocking the Periostin receptors on these neurons reduced the itch response in a mouse model.
Related publications: Periostin, an Emerging Player in Itch Sensation.
https://lnkd.in/g8dwQ3z
Periostin Activation of Integrin Receptors on Sensory Neurons Induces Allergic Itch.
https://lnkd.in/gMyJM3X
PERIOSTIN can reliably be measured by ELISA . Only 10 µl of sample volume is required! https://buff.ly/35zhkBz
Biomedica Periostin ELISA – Features & Benefits
√ CONVENIENT – Assay range optimized for clinical samples
√ RELIABLE – Full validation package
√ SPECIFIC – Characterized, epitope mapped capture and detection antibodies
√ HIGH QUALITY GUARANTEED– https://lnkd.in/gmGhJgR